In a mixing bowl, whisk together the apple juice, apple cider vinegar, Worcestershire sauce, garlic powder, onion powder, smoked paprika, brown sugar, black pepper, and salt.

Fill your injection syringe or injector with the mixture.

Insert the injector into various areas of the pork shoulder, injecting the mixture as you go.

Place the injected pork shoulder in a container and let it marinate for at least 2 hours, preferably overnight.

Preheat your smoker or oven to 225°F to 250°F.

Place the pork shoulder in the cooking device and cook until it reaches an internal temperature of 195°F to 205°F.

Remove the pork shoulder from the heat and let it rest for at least 30 minutes.

Slice the pork shoulder and serve it with your favorite sides.