Preheat the oven to 350°F (175°C).

Lightly grease a loaf pan with cooking spray or olive oil.

In a large mixing bowl, combine ground beef, breadcrumbs, eggs, chopped onion, minced garlic, ketchup, Worcestershire sauce, salt, pepper, and Italian seasoning. Mix until just combined.

Transfer the meat mixture to the prepared loaf pan, pressing it down to form a uniform shape.

Spread a thin layer of ketchup on top of the meatloaf for a glaze.

Bake in the preheated oven for 1 hour, or until the internal temperature reaches 160°F (70°C).

Remove the meatloaf from the oven and let it rest for 10 minutes.

Slice the meatloaf with a sharp knife and serve warm.