Preheat the grill to medium-high heat.

In a bowl, combine the ground beef, garlic powder, onion powder, salt, and pepper.

Divide the beef mixture into four equal portions and shape them into patties.

Make a slight indentation in the center of each patty.

Place the patties on the grill and cook for about 4-5 minutes on each side.

If using cheese, place a slice on each patty during the last minute of cooking.

Toast the buns cut-side down on the grill for about 1-2 minutes.

Assemble the burgers with cooked patties, cheese, and your favorite condiments.

Serve hot off the grill.