Start by measuring out all your ingredients.

In a mixing bowl, combine brown sugar, paprika, black pepper, kosher salt, chili powder, garlic powder, onion powder, and cayenne pepper.

Use a whisk or fork to combine the ingredients thoroughly.

If desired, taste a small amount of the rub and adjust any ingredient to suit your palate.

Transfer the rub to an airtight container for storage.

Generously rub the mixture all over your brisket.

Allow the rubbed brisket to rest for at least an hour, or preferably overnight in the refrigerator.

Cook your brisket using your preferred method.